ea0029p1612 | Thyroid (non-cancer) | ICEECE2012
Agretti P.
, Ferrarini E.
, Rago T.
, Candelieri A.
, De Marco G.
, Dimida A.
, Niccolai F.
, Molinaro A.
, Di Coscio G.
, Pinchera A.
, Vitti P.
, Tonacchera M.
Objective: MicroRNAs (miRNAs) are small endogenous non-coding RNAs that pair with target messengers regulating gene expression. They are involved in biological processes including development, organogenesis, tissue differentiation, cell cycle and metabolism. Changes in miRNA levels occur in human cancers, including thyroid cancer. Fine needle aspiration (FNA) with cytologic evaluation is the most reliable tool for malignancy prediction in thyroid nodules, but cytologic diagnos...